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Can Endometriosis Cause Gastrointestinal Symptoms?

August 18, 2025

Endometriosis, a chronic condition where tissue similar to the lining of the uterus grows outside the womb, affects approximately 10% of women of reproductive age globally. While it’s commonly associated with pelvic pain and infertility, its impact on the gastrointestinal (GI) system is less recognized but equally significant. In this article, we delve into the intricate relationship between endometriosis and GI symptoms, exploring how this condition manifests in the bowels, its symptoms, diagnosis, and available treatments.

Endometriosis and Gastrointestinal Symptoms

Individuals with endometriosis often experience a range of GI symptoms, including abdominal pain, bloating, diarrhea, constipation, nausea, and gastrointestinal discomfort. Studies estimate that up to 90% of individuals with endometriosis experience GI symptoms. These symptoms vary in intensity and often coincide with menstruation due to hormonal fluctuations.

  • Abdominal Pain: Abdominal pain, may intensify during menstruation or bowel movements. This pain arises from endometrial-like tissue in the pelvic cavity, causing inflammation, adhesions, and nerve sensitization.
  • Bloating: Hormonal fluctuations or dietary factors may exacerbate it. The exact mechanisms are not fully understood but likely involve hormonal imbalances and altered gut motility.
  • Diarrhea and Constipation: Alterations in bowel habits, including diarrhea and constipation, affect around 30-40% of individuals. These symptoms may occur cyclically or persistently throughout the menstrual cycle. Bowel endometriosis, infiltrating endometrial-like tissue into the bowel wall, contributes by causing inflammation, spasms, and transit time changes.
  • Rectal Bleeding: Rectal bleeding, though less common, occurs in approximately 20-25% of bowel endometriosis cases. Endometrial implants in the rectum or lower bowel lead to irritation, ulceration, and subsequent bleeding.
  • Nausea and Vomiting: Though less prevalent, nausea and vomiting can accompany severe abdominal pain or bloating. While the exact mechanisms are unclear, they likely involve visceral hypersensitivity and autonomic nervous system dysregulation.

Why is Endometriosis often Misdiagnosed?

However, diagnosing these symptoms can be challenging due to overlaps with other GI conditions like irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or colon cancer. Accurate diagnosis necessitates thorough evaluation by healthcare professionals.

Endometriosis vs Other Digestive Disorders

  • Irritable Bowel Syndrome (IBS): Both endometriosis and IBS can cause abdominal pain, bloating, and changes in bowel habits. However, in endometriosis, these symptoms may worsen during menstruation and may be accompanied by pelvic pain, which is not typically seen in IBS.
  • Inflammatory Bowel Disease (IBD): Symptoms like abdominal pain, diarrhea, and rectal bleeding are common in both endometriosis and IBD. However, while IBD primarily affects the colon and rectum, endometriosis-related symptoms can involve the entire GI tract.

Understanding Endometriosis in the Bowels

Complex mechanisms underline the relationship between endometriosis and GI symptoms. Endometrial-like tissue outside the uterus triggers inflammation, irritation, and scarring in nearby organs, including the bowel—termed bowel endometriosis. This results in diverse GI symptoms, including painful bowel movements, bloating, diarrhea, constipation, rectal bleeding, nausea, and vomiting. While the exact cause remains unclear, hormonal imbalances, genetic predisposition, and immune system dysfunction are believed to play roles in its development.

Surgical Treatment for Bowel Endometriosis

Once diagnosed, effective management of bowel endometriosis typically involves a multidisciplinary approach. Treatment options usually involve minimally invasive laparoscopic surgeries to remove lesions and scar tissue. In severe cases, bowel resection surgery may be necessary to alleviate symptoms and improve overall well-being.

Seeking Care with Endometriosis and GI Issues

Endometriosis and associated GI symptoms present formidable challenges. Raising awareness, recognizing symptoms, and seeking prompt medical intervention are pivotal. Comprehensive care from a multidisciplinary team, comprising gynecologists and colorectal surgeons, ensures tailored treatment addressing both gynecological and gastrointestinal facets.

Contact our team at 310-861-7493 to schedule a consultation with our bowel endometriosis experts. With proactive care and support, individuals can mitigate symptoms, enhance quality of life, and navigate the complexities of living with endometriosis.